Identification of a gene encoding TULP2, a retina specific protein
AssigneesSequana Theraputics, Inc., Jackson Lab.
InventorsMichael North, Patsy Nishina, Juergen Naggert
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Abstract
The gene responsible for an autosomal dominant con-rod retinal dystrophy is identified, TULP2. The genes are used to produce the encoded protein; in screening for compositions that modulate the expression or function of TULP2 protein; and in studying associated physiological pathways.
Claims6
An isolated nucleic acid molecule or complement thereof consisting of a nucleic acid sequence encoding a human TULP2 protein wherein the protein has the amino acid sequence of SEQ ID NO:2.
A hybridization probe consisting of at least 25 contiguous nucleotides of SEQ ID NO:
- 1 or the complement thereof, wherein said probe specifically hybridizes to SEQ ID NO:
- 1.
A hybridization probe consisting of at least 50 contiguous nucleotide of SEQ ID NO:
- 1 or the complement thereof, wherein said probe specifically hybridizes to SEQ ID NO:
- 1.
Dependencies are inferred from the claim text.