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AssigneeParhelion Corporation
InventorsRichard G. Olsen, John L. Ridihalgh
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The present invention broadly relates to a therapeutic agent effective in mitigating disease associated with Feline Leukemia Virus (FeLV) in a feline infected with FeLV. A feline is an animal of the family Felidae. The novel therapeutic agent is composed of feline excised lymph nodes which have been subjected to mitogenic stimulation for their expansion dispersed in a pharmaceutically-acceptable carrier. Mitogenic stimulation conditions include culturing the excised lymph nodes in the presence of Interleukin-2. Optionally, culture conditions can include the presence of allogeneic or autologous FeLV tumor. The inventive therapeutic agent is prepared by excising lymph nodes from a feline infected the FeLV, mitogenically stimulating said excised lymph nodes for their expansion, and administering to the infected feline the expanded lymph nodes. Multidose regimens can be used as is necessary or desirable in convenient fashion. The method for mitigating disease associated with Feline Leukemia Virus (FeLV) in a feline infected with FeLV is composed of administering to the diseased feline the therapeutic agent composed of feline excised lymph nodes which have been subjected to mitogenic stimulation for their expansion dispersed in a pharmaceutically-acceptable carrier.
A method for mitigating disease associated with Feline Leukemia Virus (FeLV) in a feline infected with FeLV, which comprises administering to said feline an effective amount of a therapeutic agent comprising lymph node lymphocytes (LNL) expressed from excised lymph nodes taken from an FeLV-infected feline in which said LNL have been subject to mitogenic stimulation by their culturing in the presence of Interleukin-2 for their expansion.
Dependencies are inferred from the claim text.