Intermediates for pyrrolidylthiocarbapenem derivative
AssigneeShionogi Seiyaku Kabushiki Kaisha
InventorsYasuhiro Nishitani, Tadashi Irie, Yutaka Nishino
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AssigneeShionogi Seiyaku Kabushiki Kaisha
InventorsYasuhiro Nishitani, Tadashi Irie, Yutaka Nishino
Estimating the term…
A pyrrolidylthiocarbapenem derivative represented by Formula I is provided: ##STR1## wherein R.sup.1 is hydrogen or lower alkyl; R.sup.2, R.sup.3 and R.sup.4 are hydrogen, lower alkyl which can be substituted or an amino protecting group independently, or R.sup.2 and R.sup.3 together with a nitrogen atom to which R.sup.2 and R.sup.3 are bonded form a saturated or unsaturated cyclic group, or R.sup.2 and R.sup.4, or R.sup.3 and R.sup.4 together with two nitrogen atoms and one sulfur atom in the sufamide group form a saturated or unsaturated cyclic group; each cyclic group can further include at least one atom selected from the group consisting of oxygen, sulfur and nitrogen, and each cyclic group can be substituted; X.sup.1 is hydrogen or a hydroxy protecting group; X.sup.2 is hydrogen, a carboxy protecting group, an ammonio group, an alkali metal or an alkaline-earth metal; and Y.sup.2 is hydrogen or an amino protecting group.
A pyrrolidine derivative represented by Formula II:
A pyrrolidine derivative represented by Formula II:
A pyrrolidine derivative represented by Formula II:
Dependencies are inferred from the claim text.