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US 5,703,108 AGranted
Bone deposition by certain prostaglandin agonists
AssigneePfizer Inc.
InventorsKimberly O. Cameron, Paul A. Dasilva-Jardine, Robert L. Rosati
Life of this patent
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Abstract
Methods for the treatment of bone disorders utilizing certain prostaglandin agonists/antagonists.
Claims16
A method for treating a mammal having a condition which presents with low bone mass comprising administering to a mammal having a condition which presents with low bone mass a therapeutically effective amount of a compound of Formula I ##STR29## or a pharmaceutically-acceptable cationic salt thereof wherein Ar is 3-thienyl, 5(C.sub.1 -C.sub.4 alkyl)-2-thienyl, 5(C.sub.1 -C.sub.4 alkyl)-3-thienyl, .alpha.-napthyl, .beta.-napthyl, tropyl, 3,4-methylenedioxyphenyl;
- R is H or methyl;
- W is a single bond or a cis double bond;
- Z is a single bond or a trans double bond;
- and
- M and Q are each independently carbonyl, ##STR30##
2 more elements
Dependencies are inferred from the claim text.