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US 5,703,104 AGranted
Cyclic amides and derivatives thereof
AssigneeDurham Pharmaceuticals LLC
InventorsJames V. Peck, Gevork Minaskanian, Mark C. Sleevi
Life of this patent
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Abstract
Compounds, topical compositions and methods useful for preventing the penetration of toxic chemicals through the skin of a mammal are disclosed. The compounds of the invention provide an enhanced barrier for the skin of a mammal to further inhibit or decrease the passage of bioactive agents through the skin of a mammal either from the outside environment into the systems of said mammal or from the mammal into the outside environment.
Claims9
A compound having one of Formulae I-IV:
- ##STR4## and pharmaceutically acceptable salts and esters thereof;
- wherein
- R is a C.sub.6-20 hydrocarbyl radical;
- X is one of --CH.sub.2 --, --NH--, --O-- or --S--.
1 more element
Dependencies are inferred from the claim text.