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US 5,703,070 AGranted
Indole, indazole and benzisoxazole compounds
AssigneeAdir et Compagnie
InventorsGilbert Lavielle, Olivier Muller, Mark Millan, Valerie Audinot
Life of this patent
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Abstract
Compound of formula (I): ##STR1## in which: R.sub.1 represents hydrogen, halogen, alkyl, alkoxy, trihalomethyl or hydroxyl, R.sub.2 represents hydrogen, alkyl or phenyl which is optionally substituted, ##STR2## or alternatively ##STR3## represents --O--N.dbd., 1.ltoreq.n.ltoreq.6, ##STR4## represents any one of the groups defined in the description, its isomers and its addition salts with a pharmaceutically acceptable acid or base, a medicinal products containing the same are useful in the treatment of schizophrenia.
Claims9
A compound selected from the group having formula (I):
- ##STR16## in which:
- R.sub.1 represents hydrogen, halogen, linear or branched (C.sub.1 -C.sub.6)alkyl, linear or branched (C.sub.1 -C.sub.6)alkoxy, trihalomethyl, or hydroxyl,
- R.sub.2 represents hydrogen or linear or branched (C.sub.1 -C.sub.6)alkyl or a phenyl group which is unsubstituted or substituted by halogen, alkyl, alkoxy, hydroxyl, or trihalomethyl, ##STR17## or represents --O--N.dbd., n is 1, 2, 3, 4, 5, or 6 ##STR18## represents any one of the following groups:
- ##STR19## in which:
- R represents hydrogen, halogen, linear or branched (C.sub.1 -C.sub.6)alkyl, linear or branched (C.sub.1 -C.sub.6)alkoxy, hydroxyl, or trihalomethyl,
- Z represents oxygen, sulfur, or --NH--,
- its isomers and its addition salts with a pharmaceutically-acceptable acid or base.
4 more elements
Dependencies are inferred from the claim text.