Loading patent…
AssigneeThe Trustees of the University of Pennsylvania
InventorsMark I. Greene, James G. Davis
Estimating the term…
A substantially purified saccular collagen protein and compositions, including pharmaceutical compositions, that comprise the saccular collagen protein are disclosed. Methods of using the saccular collagen which comprise injecting the saccular collagen into the tissue of an individual are disclosed. Antibodies which bind to the saccular collagen protein, nucleic acid molecules which encode the saccular collagen protein, and oligonucleotides which are identical or complementary to at least a portion of the sequence that encodes the saccular collagen proteins are disclosed. Recombinant expression vector that comprise nucleic acid molecules that encode the saccular collagen protein and host cells, including the cells of transgenic animals, which comprise the recombinant expression vectors are disclosed.
An isolated nucleic acid molecule comprising a nucleotide sequence that encodes the protein having the amino acid sequence of SEQ ID NO:2.
A recombinant expression vector comprising a nucleotide sequence that encodes the protein having the amino acid sequence of SEQ ID NO:2.
An isolated oligonucleotide molecule comprising a nucleotide sequence complementary to a nucleotide sequence of at least 50 nucleotides of SEQ ID NO:1.
An oligonucleotide molecule comprising a nucleotide sequence complementary to a nucleotide sequence of at least 10 nucleotides of SEQ ID NO:1 between nucleotide 331 and nucleotide 501 of SEQ ID NO:1, or between nucleotide 1600 and nucleotide 1839 of SEQ ID NO:1.
Dependencies are inferred from the claim text.