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US 5,702,938 AGranted
Human tissue plasminogen activator
AssigneeGenetech, Inc.
InventorsDavid V. Goeddel, William J. Kohr, Diane Pennica, Gordon A. Vehar
Life of this patent
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Abstract
Human tissue plasminogen activator (t-PA) is produced in useful quantities using recombinant DNA techniques. The invention disclosed thus enables the production of t-PA free of contaminants with which it is ordinarily associated in its native cellular environment. Methods, expression vehicles and various host cells useful in its production are also disclosed.
Claims4
A DNA molecule which is a cDNA molecule or a recombinant DNA molecule encoding an amino acid sequence comprising the presequence of human tissue plasminogen activator.
Dependencies are inferred from the claim text.