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AssigneeSeikagaku Kogyo Kabushiki Kaisha (Seikagaku Corporation)
InventorsHiroshi Tamura, Toshio Oda, Shigenori Tanaka
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Endotoxin (Et) can be specifically assayed by exclusively utilizing the factor C system reaction without being affected by factor G contained in a limulus amebocyte lysate reagent. The present invention provides: (1) a reagent for ET-specific assay which comprises a limulus amebocyte lysate reagent and an alkylglucoside; (2) a method of specifically assaying Et in a specimen using a limulus amebocyte lysate reagent, wherein an alkylglucoside is added to the limulus amebocyte lysate reagent and/or the specimen; and (3) a factor G activation inhibitor composition which comprises an alkylglucoside as an active ingredient capable of inhibiting the activation of factor G in limulus amebocyte by (1.fwdarw.3)-.beta.-D-glucan.
A reagent for endotoxin-specific assay which comprises a limulus amebocyte lysate reagent and an alkylglucoside.
A method of assaying for endotoxin in a specimen using a limulus amebocyte lysate reagent, comprising the steps of:
A kit for endotoxin-specific assay which comprises a limulus amebocyte lysate reagent and a reagent containing an alkylglucoside.
A factor G activation inhibitor composition which comprises an alkylglucoside as an active ingredient capable of inhibiting the activation of factor G existing in limulus amebocyte by (1.fwdarw.3)-.beta.-D-glucan and, water or a buffer agent free from endotoxin.
A method for inhibiting activation of factor G existing in a limulus amebocyte lysate reagent comprising the step of adding an alkylglucoside to the limulus amebocyte lysate reagent.
Dependencies are inferred from the claim text.