Salmonicida iron regulated protein and lipopolysaccharide vaccine
AssigneeThe Secretary of State for Scotland in Her Britannic Majesty's Government of the United Kingdom of Great Britain and Northern Ireland
InventorAnthony E. Ellis
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Abstract
A treatment of fish for infection by the organism Aeromonas salmonicida using either one or both of two components produced by a culture of the organism. The culture is treated to kill the organisms prior to use, preferably by treatment with formalin after the components have been produced. One of the components, only produced when the culture is grown under iron limiting conditions induces production of antibodies which cause death of the organisms when injected intraperitoneally into fish.
Claims8
A method of protecting fish from or treating fish having an Aeromonas salmonicida evoked disease comprising administering to said fish an effective amount of iron regulated outer membrane proteins as a vaccine active component.
A method of protecting fish from or treating fish having an Aeromonas salmonicida evoked disease comprising administering to said fish an effective amount of iron regulated outer membrane proteins and external lypolysaccharides as a vaccine active component.
A composition comprising iron regulated outer membrane proteins of Aeromonas salmonicida and adjuvant in a form suitable for administration to an animal body for raising antibodies to said iron regulated outer membrane proteins without causing infection with that organism.
A composition comprising iron regulated outer membrane proteins of Aeromonas salmonicida in a form suitable for administration to an animal body for raising antibodies to said iron regulated outer membrane proteins without causing an infection with that organism, wherein the iron regulated outer membrane proteins are in the form selected from the group consisting of an inactivated whole cell membranes, inactivated whole cell outer membranes and inactivated whole cells.
Dependencies are inferred from the claim text.