Diagnostic method and test kit for the serological detection of the AIDS virus
AssigneeViral Technologies, Inc.
InventorsAllan L. Goldstein, Su Sun Wang
Life of this patent
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Abstract
A peptide of up to about 40 amino acids including the core sequence inclusive of amino acids at positions 92-109 of the p17 gag core protein of HIV-1, such as, Ile-Y.sub.1 -Y.sub.2 -Lys-Asp-Thr-Lys-Glu-Ala-Leu-Y.sub.3 -Lys-Ile-Glu-Glu-Glu-Gln-Asn wherein Y.sub.1 is Asp or Glu, Y.sub.2 is Val or Ile, and Y.sub.3 is Glu or Asp, is effective in inhibiting replication of the HIV virus and provides the basis for a vaccine for treatment or prevention of AIDS.
Claims9
A peptide of at least about 18 and up to about 40 amino acids including the sequence extending from position 92 to position 109 of the p17 gag protein of HIV-1 and wherein the sequence may be extended from either or both the N-terminal and the C-terminal to include one or more additional consecutive amino acids of the p17 protein of HIV-1, wherein the total number of amino acids in said peptide does not exceed about 40.
Dependencies are inferred from the claim text.