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US 5,702,682 AGranted
Methods for preparing radiopaque medical devices
AssigneeHercules Incorporated
InventorSamuel Anthony Thompson
Life of this patent
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Abstract
Disclosed is a method for providing radiopacity to a medical device comprising incorporating in said medical device metal-cation salt of anionic polymer, wherein the metal has atomic weight greater than about 40; radiopaque medical devices comprising the essentially water-insoluble metal-cation salts of anionic polymers; and a method for carrying out x-ray diagnostic procedures comprising administering to a subject a contrast agent comprised of the essentially water-insoluble metal-cation salts of anionic polymer.
Claims24
A method for increasing the radiopacity of a medical device comprising:
- (a) providing:
- (i) a medical device comprising a cation salt of an anionic polymer and (ii) an aqueous solution of a water-soluble composition containing metal-cations of atomic weight greater than about 40;
- and
- (b) soaking said medical device in said aqueous solution for a time effective to replace at least a portion of the cations in the medical device with said metal-cations to form an essentially water-insoluble metal-cation salt of anionic polymer dispersed within said medical device, thereby obtaining a medical device with increased radiopacity.
1 more element
Dependencies are inferred from the claim text.