Production of fine particle dye or drug preparations
AssigneeBASF SE
InventorsLutz End, Dieter Horn, Erik Lueddecke
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Abstract
Process for the production of fine-particle, essentially amorphous dye or drug preparations by converting a relatively coarse-particle dispersion or a solution into a colloidal dispersion in water, where the colloidal dispersion is generated at a temperature above the melting point of the dye or drug by admixing appropriately hot water (where appropriate under pressure) or an aqueous protective colloid solution so that an emulsion of a melt in aqueous medium is produced and is immediately spray-dried or converted by cooling into a suspension.
Claims4
A process for producing fine-particle, essentially amorphous dye or drug preparations by converting a relatively coarse-particle aqueous dispersion or an organic solution in a solvent dissolving to an extent of at least 10% in water into a colloidal dispersion in water, wherein the aqueous dispersion or organic solution of the dye or drug is subjected to turbulent mixing at a temperature above the melting point of the dye or drug, where appropriate under pressure, with water or an aqueous protective colloid solution, and the resulting melt emulsion is immediately spray-dried or converted into a suspension by cooling.
Dependencies are inferred from the claim text.