Extracts of ginkgo biloba and their methods of preparation
AssigneeIndena S.p.A.
InventorsEzio Bombardelli, Giuseppe Mustich, Marco Bertani
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Abstract
A process is provided for producing a purified extract from Ginkgo biloba leaves by solvent extraction with selected solvents. In the process, a crude or partially purified extract is subjected to solvent extraction with a solvent comprising toluene and n-butanol. Pharmaceutical compositions comprising dimeric flavones and/or polyphenols are also described.
Claims2
A composition comprising compounds extracted from leaves of Ginkgo biloba and wherein inactive lipophilic substances which can be extracted by n-hexane, n-heptane or a solvent comprising toluene and n-butanol wherein the volume ratio of toluene:butanol is from 6:1 to 12:1 are absent, said composition including the following components:
- ______________________________________ ginkgo flavone glucosides 24 wt % proanthocyanidines 9 wt % ginkgolides 3.6 wt % bilobalide 3.1 wt % sulphuric ash 0.1 wt %. ______________________________________
Dependencies are inferred from the claim text.