Fluorescence detector, and a device for supporting a replacable sample cuvette in a fluorescence detector
AssigneeCMA/Microdialuysis Research AB
InventorLeon Carlson
Life of this patent
Estimating the term…
Abstract
A fluorescence detector has a light source in the form of a halogen lamp, a UV-filter which allows excitation radiation in UV to pass through, and a second filter which sorts out fluorescence radiation, and a detector which detects the through-passing fluorescence radiation. The filters comprise thin straight blocks and also function as light guides and are positioned at right angles with their extensions directed towards a point at which a tubular sample can be placed in close with the ends of the filters distal from the light source and the detector.
Claims13
In a fluorescence detector for measuring fluorescence in a liquid comprising a light source for irradiating the liquid with fluorescence generating radiation, a filter for allowing fluorescence radiation generated by liquid to pass through, and a detector for detecting fluorescence radiation that has passed through the filter and for producing an electric signal corresponding to the fluorescence radiation, the improvement comprising:
- an elongated, flat-shaped first light conductor having a first end in proximity to the light source, and a second end adapted to be positioned in proximity to an irradiated region of a liquid-containing tube having an inner diameter approximating the thickness of the first light conductor, said first light conductor having a length which is at least 10 times said thickness, and functioning as a filter to provide a first filter effect which is pervious to ultraviolet light but impervious to wavelength ranges of generated fluorescence radiation;
- an elongated, flat-shaped second light conductor having a first short side in proximity to the detector, and a second short side adapted to be positioned in proximity to a detection region of the tube whose inner diameter approximates the thickness of the second light conductor, said second light conductor having a length which is at least 6 times that of its thickness, said second light conductor being pervious to fluorescence radiation and functioning as a filter to provide a second filter effect;
- wherein the light conductors are positioned with their longitudinal axes in mutual transverse directions, and wherein in use, the second end of the first light conductor and the second short side terminate almost tangentially with the outer surface of the tube, and the irradiated region and the detection region coincide at least partially in the longitudinal direction of the tube.
Dependencies are inferred from the claim text.