Porcine adipocyte antigens and their use in the immunological control of fat
AssigneeBritish Technology Group Limited
InventorsAnthony Cryer, David J. Flint, Steven C. Kestin
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Abstract
Antigens present in the plasma membrane of mature porcine white adipocytes, which are not present in porcine liver, kidney, spleen, brain, cardiac muscle, skeletal muscle or lung or in porcine erythrocytes, which react with antisera raised against said adipocytes and which on SDS-PAGE give rise to protein bands of relative molecular mass (r.m.m.) about 37, 50, 51 and 121 KiloDaltons, respectively and antibodies thereto are useful for the reduction of fat in pigs.
Claims6
An isolated antigen present in the plasma membrane of mature porcine white adipocytes, which is not detectable in porcine liver, kidney, spleen, brain, cardiac muscle, skeletal muscle or lung or in porcine erythrocytes, which reacts with antisera raised against said adipocytes, said antigen being selected from the group consisting of a 37, 50, 51, and 121 KiloDaltons relative molecular mass antigen as determined by SDS-PAGE using markers of relative molecular mass 29, 45, 66, 97, 116, and 205 KiloDaltons.
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