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US 5,352,840 AGranted
Oxidation process
AssigneeSolvay Interox Limited
InventorsStephen G. Grundy, Kevan M. Reeve, Michael C. Rocca
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AssigneeSolvay Interox Limited
InventorsStephen G. Grundy, Kevan M. Reeve, Michael C. Rocca
Estimating the term…
Substituting aqueous hydrogen peroxide/hydrogen bromide for bromine in a known process for producing a ditertiaryalkyl substituted hydroxybenzaldehyde such as ditertiarybutyl hydroxybenzaldehyde from the corresponding ditertiaryalkyl substituted methylphenol results in a substantially impaired yield of product. Improved yields are obtained by employing a reaction temperature of at least 40.degree. C., preferably 50.degree. to 80.degree. C. in conjunction with a hydrophobic solvent such as chloroform. Preferably, the process employs very concentrated hydrogen peroxide solution, 65% to 75% w/w, introduced into the bromide-containing reaction mixture during a period of from 25 to 75 minutes.
A process for the production of a 3,5-ditertiaryalkyl-4-hydroxybenzaldehyde from a 2,6-ditertiary alkyl-4-methylphenol by reaction with aqueous hydrogen bromide and hydrogen peroxide characterised by conducting the reaction in the presence of a hydrophobic solvent at a reaction temperature selected between 40.degree. C. and the boiling point of the reaction mixture.
Dependencies are inferred from the claim text.