Thiophene-2-carboxylic acid derivatives
AssigneeLaevosan Gesellschaft m. b. H.
InventorsGerhard Greier, Dieter Binder
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Abstract
There are described novel compounds of the general formula ##STR1## in which R in position 3 or 4 is hydrogen, methyl, chlorine or bromine and R.sup.2 is C.sub.1 -C.sub.10 -alkyl, C.sub.3 -C.sub.7 -cycloalkyl or benzyl, and the pharmaceutically acceptable addition salts thereof with weak organic acids as well as a process for the preparation thereof. The compounds of formula (I) are inhibitors of thromboxane synthetase.
Claims5
A compound of formula (I) ##STR6## in which R in position 3 or 4 is hydrogen, methyl, chlorine or bromine and R.sup.2 is C.sub.1 -C.sub.10 -alkyl, C.sub.3 -C.sub.7 - cycloalkyl or benzyl, or a pharmaceutically acceptable addition salt thereof with weak organic acids.
1-Ethoxycarbonyloxyethyl ester of 5-[2-(1H-imidazole-1-yl)-ethoxyl]-thiophene-2-carboxylic acid.
1-Ethoxycarbonyloxyethyl ester fumarate of 5-[2-(1H-imidazole-1-yl)-ethoxy]-thiophene-2-carboxyl acid.
Dependencies are inferred from the claim text.