Substituted phenylacetamides

A substituted phenylacetamide of the formula ##STR63## in which A represents straight-chain or branched alkyl or alkenyl each having up to 8 carbon atoms, or represents cycloalkyl having 3 to 8 carbon atoms,

• R represents hydrogen, halogen or perfluoroalkyl having up to 5 carbon atoms,
• D represents a group of the formula --CH.sub.2 OR.sup.3, --CO--R.sup.4, --CO--NR.sup.5 R.sup.6, ##STR64## in which R.sup.3 denotes hydrogen or straight-chain or branched alkyl having up to 8 carbon atoms,
• R.sup.4 represents hydrogen, hydroxyl or straight-chain or branched alkoxy having up to 8 carbon atoms,
• R.sup.5 and R.sup.6 are identical or different and denote hydrogen, straight-chain or branched alkyl having up to 8 carbon atoms, or
• R.sup.5 has the abovementioned meaning and
• R.sup.6 denotes a group of the formula --SO.sub.2 R.sup.12, in which
• R.sup.12 denotes straight-chain or branched alkyl having up to 6 carbon atoms, or benzyl or phenyl which are optionally substituted by straight-chain or branched alkyl having up to 6 carbon atoms,
• a and b are identical or different and denote a number 0, 1 or 2,
• R.sup.7 denotes hydrogen or straight-chain or branched alkyl having up to 8 carbon atoms or a hydroxyl protective group selected from the group consisting of trimethylsilyl, triethylsilyl, triisopropylsilyl, tert-butyldiphenylsilyl, tert-butyldiphenylsilyl, trimethylsilylethoxycarbonyl, benzyl, triphenylmethyl(trityl), monomethoxytrityl (MMTr), dimethoxytrityl (DMTr), benzyloxycarbonyl, 2-nitrobenzyl, 4-nitrobenzyl, 2-nitrobenzyloxycarbonyl, 4-nitrobenzyloxycarbonyl, tert-butyloxycarbonyl, 4-methoxybenzyl, 4-methoxybenzyloxycarbonyl, formyl, acetyl, trichloroacetyl, 2,2,2-trichloroethoxycarbonyl, 2,4dimethoxybenzyl, 2,4-dimethoxybenzyloxycarbonyl, methoxymethyl, methylthiomethyl, methoxyethoxymethyl, [2-(trimethylsilyl)ethoxy]methyl, 2-(methylthiomethoxy)ethoxycarbonyl, tetrahydropyranyl, benzoyl, 4-methylbenzoyl, 4-nitrobenzoyl, 4-fluorobenzoyl, 4-chlorobenzoyl, and methoxybenzoyl,
• R.sup.8 and R.sup.10 are identical or different and denote hydrogen, straight-chain or branched alkyl having up to 6 carbon atoms, cycloalkyl having 3 to 8 carbon atoms, phenyl or thienyl,
• R.sup.9 and R.sup.11 are identical or different and denote hydrogen or straight-chain or branched alkyl having up to 8 carbon atoms,
• E represents hydrogen, halogen, nitro, hydroxyl, trifluoromethyl, trifluoromethoxy, straight-chain or branched alkyl, alkoxy or alkoxycarbonyl each having up to 6 carbon atoms, cyano or carboxyl,
• L represents straight-chain or branched alkyl having up to 8 carbon atoms, which is optionally substituted by cycloalkyl having 3 to 8 carbon atoms or by phenyl, represents cycloalkyl having 3 to 12 carbon atoms, which is optionally substituted by straight-chain or branched alkyl having up to 6 carbon atoms,
• R.sup.1 represents hydrogen or straight-chain or branched alkyl having up to 8 carbon atoms,
• R.sup.2 represents pyridyl, morpholinyl, tetrahydropyranyl, tetrahydrofuranyl, quinolinyl, dihydrobenzopyranyl or dihydrobenzofuranyl, which is optionally substituted up to 3 times by identical or different substituents from the group consisting of nitro, cyano, halogen, hydroxyl, trifluoromethyl, carboxyl, straight-chain or branched alkoxy or alkoxycarbonyl each having up to 6 carbon atoms, phenoxy, benzyloxy, phenoxycarbonyl and benzyloxycarbonyl, or represents a radical of the formula ##STR65## in which R.sup.13 denotes phenyl which is optionally substituted up to 3 times by identical or different substituents from the group consisting of halogen, hydroxyl and trifluoromethyl or by straight-chain or branched alkyl or alkoxy each having up to 8 carbon atoms,
• c, d, e and f are identical or different and denote a number 0, 1, 2, 3 or 4,
• R.sup.14 denotes hydrogen, trifluoromethyl, carboxyl or straight-chain or branched alkoxycarbonyl having up to 8 carbon atoms or the group --CO--NH.sub.2 or pyridyl or morpholinyl, or a salt thereof.