Process for producing 3-hydroxymethyl-1-propargylimidazolidine-2,4-dione
AssigneeSumotomo Chemical Company, Ltd.
InventorsYoo Tanabe, Masanari Murakami, Hitomi Yamamoto
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Abstract
Disclosed is a process for producing 3-hydroxymethyl-1-propargylimidazolidine-2,4-dione which comprises (i) reacting a compound of the formula (I) ##STR1## wherein R represents an alkyl, alkoxyalkyl or aralkyl group with a compound of the formula (II) CH.ident.C--CH.sub.2 --X (II) wherein X represents a leaving group in the presence of a base to give a 1-propargylimidazolidine-2,4-dione derivative of the formula (III) ##STR2## wherein R is as defined above and (ii) hydrolyzing this derivative of the formula (III).
Claims11
A process for producing 3-hydroxymethyl-1-propargylimidazolidine -2,4-dione which comprises:
- (i) reacting a compound of the formula (I) ##STR6## wherein R represents an alkyl, alkoxyalkyl or aralkyl group with a compound of the formula (II)
- CH.ident.C--CH.sub.2 --X (II)
- wherein X represents a halogen atom or sulfonic acid residue in the presence of a base to give a 1-propargylimidazolidine -2,4-dione derivative of the formula (III) ##STR7## wherein R is as defined above, and (ii) hydrolyzing this derivative of the formula (III).
A process for producing 3-hydroxymethyl-1-propargylimidazolidine-2,4-dione which comprises:
- (i) reacting imidazolidine-2,4-dione with a compound of the formula (IV)
- Y--CH.sub.2 OR (IV)
- wherein R represents an alkyl group, an alkoxyalkyl group or an aralkyl group and Y represents a halogen atom to obtain a compound of the formula (I):
- ##STR8## wherein R represents an alkyl, alkoxyalkyl or aralkyl group, (ii) reacting a compound of the formula (I) with a compound of the formula (II)
- CH.ident.C--CH.sub.2 --X (II)
- wherein X represents a halogen atom or sulfonic acid residue in the presence of a base to give a 1-propargylimidazolidine-2,4-dione derivative of the formula (III) ##STR9## wherein R is as defined above, and (iii) hydrolyzing this derivative of the formula (III).
Dependencies are inferred from the claim text.