Derivatized D-acyl pyridinium reagent
AssigneeMetra Biosystems, Inc.
InventorsYuri Daniloff, Simon P. Robins, Brian J. Evans, David A. Pratt, Robert Lungard
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Abstract
O-acylated pyridinium compounds in which the 3-hydroxy moiety derivatized specifically at its aliphatic hydroxyl group by a selected acyl group is disclosed. In various embodiments, the composition may be used as a standard for HPLC or immunoassay of pyridinoline, a pyridinoline immunogen for producing anti-pyridinoline antibodies, and a solid-phase reagent for use in an immunoassay kit. Also disclosed are methods for making and using the composition.
Claims4
An O-acylated pyridinium compound having the following structure:
- ##STR2## where R is an acyl group.
An O-acylated pyridinium compound having the following structure:
- ##STR3## where R is an acetyl or propionyl group.
Dependencies are inferred from the claim text.