Unguinol and analogs are animal growth permittants
AssigneeMerck & Co., Inc.
InventorsScott D. Feighner, Gino M. Salituro, Jack L. Smith, Nancy N. Tsou
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AssigneeMerck & Co., Inc.
InventorsScott D. Feighner, Gino M. Salituro, Jack L. Smith, Nancy N. Tsou
Estimating the term…
Unguinol is a well-known metabolite of the fungi Aspergillus unguis and Aspergillus nidulans. Unguinol has been found to be an active growth permittant and promotant in animals, in particular, monogastric animals such as chickens. In addition, the fermentation broth also produced the additional known unguinol derivatives of folipastatin and 2-chloro unguinol as well as the novel 4-methyl derivative. All of these compounds are active animal growth permittants. Compositions containing such unguinol derivatives for use as growth permittants and promotants are also disclosed.
A method for promoting the growth of animals and for increasing the efficiency of feed utilization of such animals which comprises administering to such animals an effective amount of unguinol, or derivatives thereof having the following structures:
A composition for promoting the growth of animals and for increasing the efficiency of feed utilization of such animals which comprise a carrier and an effective amount of unguinol derivative having the following structure:
A compound having the formula ##STR5## which is 4-methyl unguinol.
Dependencies are inferred from the claim text.