Back to results
US 5,349,047 AGranted
Polyesters having predetermined monomeric sequence
AssigneeUnited States Surgical Corporation
InventorsMatthew E. Hermes, Bin Huang
Life of this patent
Estimating the term…
Abstract
Polyesters having predetermined monomeric sequence are produced by stepwise addition of monomeric hydroxyacids to a growing polymeric chain. Included herein are various polyesters having predetermined primary sequence, various methods of producing polyesters having predetermined primary sequence, various articles formed from polyesters having predetermined primary sequence and various methods of using such articles.
Claims29
A process for making a polyester having a predetermined monomeric sequence comprising:
- (i) providing an aliphatic ester of a first hydroxyacid;
- (ii) protecting a hydroxyl group on said aliphatic ester of a first hydroxyacid with a hydroxyl protecting group;
- (iii) subjecting said hydroxyl-protected aliphatic ester of a first hydroxyacid to hydrolysis to remove the aliphatic ester substituent;
- (iv) protecting a carboxyl group on a next hydroxyacid with a carboxyl protecting group;
- (v) reacting said first hydroxyl-protected hydroxyacid with said next carboxyl-protected hydroxyacid;
- and
- (vi) forming a product having an ester bond between said first hydroxyl-protected hydroxyacid and said next carboxyl-protected hydroxyacid.
4 more elements
Dependencies are inferred from the claim text.