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US 5,347,075 AGranted
Mutagenesis testing using transgenic non-human animals carrying test DNA sequences
AssigneeStratagene
InventorJoseph A. Sorge
Life of this patent
Estimating the term…
Abstract
An assay for monitoring and assessing the mutagenic potential of agents which involves creating transgenic non-human animals carrying a test DNA sequence or sequences that can be quickly recovered and examined for mutations following exposure to one or more suspected mutagenic agents.
Claims3
A transgenic mouse whose somatic and germ cells contain the beta-galactosidase gene flanked by the bacteriophage lambda cos sites, and the expression of said beta-galactosidase gene being capable of detection in E. coli.
Dependencies are inferred from the claim text.