US 5,347,037 A · (RR) and (RS stereoisomers of N-(7-ethoxycarbonylmethoxy-1,2,3,-tetrahydronaphth-2-yl)-2-(3-chlorophen yl)-2-hydroxyethanamine and their pharmaceutically acceptable salts

Abstract

A process for the preparation of a compound of formula (I) ##STR1## which is a (RR) and (RS) stereoisomer of N-(7-ethoxycarbonylmethoxy-1,2,3,4,-tetrahydronaphth-2-yl)-2-(3-chlorophen yl)-2-hydroxyethanamine and their pharmaceutically acceptable salts.

Claims2

Dependent claims

A substantially optically pure compound which is N-[(2S)-7-ethoxycarbonylmethoxy-1,2,3,4-tetrahydronaphth-2-yl]-(2R)-2-(3-c hlorophenyl)-2-hydroxyethanamine and its pharmaceutically acceptable salts.

Dependencies are inferred from the claim text.

Facts

Application

08/114,190Filed 1 Sep 1993 · continuation

Priority

FR 87 1149812 Aug 1987

Granted

13 Sep 1994

Term ends

Not estimatedThe source records don’t support an estimate.

Classification6 codes

C07C 213/06
Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same…:…
C07C 217/74
Having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms…:…
C07C 271/16
With the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms: to carbon atoms of hydrocarbon radicals…
C07C 271/24
Having oxygen atoms of carbamate groups bound to acyclic carbon atoms: with the nitrogen atom of at least one of the carbamate groups bound to a…

Family

Serial230,860Parent of this division · filed 11 Aug 1988

Serial488,137Parent of this division · filed 5 Mar 1990

Serial698,087Parent of this continuation · filed 10 May 1991

Serial909,315Parent of this continuation · filed 6 Jul 1992

US 5,041,606 AParent of this division

US 4,927,955 AParent of this division

US 5,347,037 AThis patent

From the US filing history. Foreign family members aren’t listed.

Abstract

Claims2

Dependent claims

A substantially optically pure compound which is N-[(2S)-7-ethoxycarbonylmethoxy-1,2,3,4-tetrahydronaphth-2-yl]-(2R)-2-(3-c hlorophenyl)-2-hydroxyethanamine and its pharmaceutically acceptable salts.

Dependencies are inferred from the claim text.

Facts

Application

08/114,190Filed 1 Sep 1993 · continuation

Priority

FR 87 1149812 Aug 1987

Granted

13 Sep 1994

Term ends

Not estimatedThe source records don’t support an estimate.

Classification6 codes

C07C 213/06
Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same…:…
C07C 217/74
Having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms…:…
C07C 271/16
With the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms: to carbon atoms of hydrocarbon radicals…
C07C 271/24
Having oxygen atoms of carbamate groups bound to acyclic carbon atoms: with the nitrogen atom of at least one of the carbamate groups bound to a…

Family

Serial230,860Parent of this division · filed 11 Aug 1988

Serial488,137Parent of this division · filed 5 Mar 1990

Serial698,087Parent of this continuation · filed 10 May 1991

Serial909,315Parent of this continuation · filed 6 Jul 1992

US 5,041,606 AParent of this division

US 4,927,955 AParent of this division

US 5,347,037 AThis patent

From the US filing history. Foreign family members aren’t listed.

(RR) and (RS stereoisomers of N-(7-ethoxycarbonylmethoxy-1,2,3,-tetrahydronaphth-2-yl)-2-(3-chlorophen yl)-2-hydroxyethanamine and their pharmaceutically acceptable salts

Life of this patent

Abstract

Claims2

(RR) and (RS stereoisomers of N-(7-ethoxycarbonylmethoxy-1,2,3,-tetrahydronaphth-2-yl)-2-(3-chlorophen yl)-2-hydroxyethanamine and their pharmaceutically acceptable salts

Life of this patent

Abstract

Claims2