Anti-fungal uracil compounds

A compound of the formula:

• ##STR125## or pharmaceutically acceptable salts thereof, wherein Het is ##STR126## R is H, COOH;
• C.sub.1 -C.sub.12 alkyl;
• CHO;
• CN;
• CH.sub.2 OH;
• or CONH.sub.2 ;
• wherein R.sub.3 is ##STR127## wherein R.sub.8 is ##STR128## R.sub.2 is H;
• OH;
• F;
• C.sub.1 -C.sub.6 alkoxy;
• alkyl;
• SH;
• S-alkyl;
• or SO.sub.2 -alkyl;
• R.sub.4 is H;
• a natural amino acid attached by a peptide bond;
• or a metabolizable group;
• J is OH, H, Br, Cl, or F;
• K is OH, H, Br, Cl, or F;
• X and Y are the same or different and are independently selected from the group consisting of H;
• OH;
• O-C.sub.1 -C.sub.14 alkyl;
• F;
• Cl;
• Br;
• NO.sub.2, and alkyl;
• Z is R.sub.5 NR.sub.6 ;
• ##STR129## wherein Z' is R.sub.5 NR.sub.6, R.sub.5 is (CH.sub.2).sub.11 CH.sub.3 ;
• R.sub.6 is H;
• OH;
• O-benzyl;
• O-aryl;
• O-C.sub.4 -C.sub.14 alkyl;
• C.sub.1 -C.sub.12 alkyl;
• phenyl;
• substituted phenyl;
• or CO-R.sub.7 ;
• and
• R.sub.7 is H, C.sub.1 -C.sub.16 alkyl, aryl or alkylaryl;
• and
• n is an integer from 0 to 16.