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US 5,346,813 AGranted
Method of screening for small cell lung carcinoma
AssigneeBoehringer Mannheim GmbH
InventorsHeinz Bodenmuller, Andreas Dessauer
Life of this patent
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Abstract
In order to detect a small cell lung carcinoma, synaptophysin, its oligomers and/or its fragments are determined in body fluids.
Claims23
A method of screening for small cell lung carcinoma comprising,
- contacting a body fluid sample with antibodies or antibody fragments which specifically bind synaptophysin,
- detecting at least one member of the group consisting of synaptophysin monomers, synaptophysin oligomers, and synaptophysin fragments,
- wherein the presence of synaptophysin in the body fluid sample is associated with the presence of small cell lung carcinoma.
A method of screening for small cell lung carcinoma comprising,
- contacting a serum sample with antibodies or antibody fragments which specifically bind synaptophysin,
- detecting at least one member of the group consisting of synaptophysin monomers, synaptophysin oligomers, and synaptophysin fragments,
- wherein the presence of synaptophysin in the serum sample is associated with the presence of small cell lung carcinoma.
Dependencies are inferred from the claim text.