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AssigneesCerveceria Polar, Universidad Central de Venezuela
InventorsIvan Galindo-Castro, Jose L. Ramirez, Rafael R. Aldao
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The present invention provides a Human Papillomavirus (HPV) detection method, the results capable of being read on specimen slides through in situ hybridization techniques. The method is based on a pair of consensus polynucleotide probes which hybridize type-specifically with clinically important HPV viral types and is capable of distinguishing between malignant and benign HPV viruses. Compositions of the polynucleotide probes in detectably labeled form are also a part of the invention. For correlation of the present method with known polymerase chain reaction (PCR) detection of HPV, a PCR assay is described.
A polynucleotide molecule comprising the sequence:
A polynucleotide molecule consisting essentially of the sequence:
The kit of claim 24 wherein said antibody is conjugated to a detectable label and binds specifically to an antigenic moiety of claim 28.
Dependencies are inferred from the claim text.