Methods of inhibiting HIV replication in vitro using polymers of p-hydroxylated cinnamic acids
AssigneeTampa Bay Research Institute
InventorsMeihan Nonoyama, Akiko Tanaka, Patrick K. Lai, Kunio Konno, Yutaka Kawazoe, Hiroshi Sakagami
Life of this patent
Estimating the term…
Abstract
Polymers of p-hydroxylated cinnamic acids and p-hydroxylated cinnamyl alcohols have potent anti-viral activity in vitro.
Claims5
A method for inhibiting replication of HIV in human cells infected with the virus which comprises contacting the cells in vitro with polymers of p-hydroxylated cinnamic acid or polymers of substituted p-hydroxylated cinnamic acid wherein the substituent is selected from the group consisting of methoxy and hydroxy groups, said polymers having molecular weights within the range of about 2,000 to about 5,000 and anti-HIV activity.
Dependencies are inferred from the claim text.