Method for producing o-alkoxybenzoic acid
AssigneeNippon Chemical Industrial Co., Ltd.
InventorsSuchart Lilitkarntakul, Shukichi Nabekawa, Masao Takada, Katsuyuki Ogura
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Abstract
o-Methoxy benzoic acid is produced by reacting chlorobenzoic acids having at least one chlorine atom at least at the ortho position with lower alcohol in the presence of a copper salt and a lower alkyl as a catalyst under moderate reaction conditions. o-Methoxy benzoic acid is useful as an intermediate for pharmaceutical, agricultural chemicals, and the like.
Claims11
A method for producing o-alkoxybenzoic acid, comprising reacting o-chlorobenzoic acid represented by the following general formula ##STR7## (wherein X is at a meta- or para position and represents hydrogen or halogen) with a lower alcohol in the presence of a copper salt and a lower alkylamine as a catalyst, wherein the reagent ratios of the copper salt, loweralkylamine and lower alcohol per 1 mol of o-dichlorobenzoic acid are in the range of 0.1-0.5 mol, 1-20 mol and 10-150 mol, respectively.
A method for producing o-dialkoxybenzoic acid, comprising reacting 2,6-dichlorobenzoic acid represented by the following general formula ##STR8## (wherein X represents hydrogen or halogen) with a lower alcohol in the presence of a copper salt and an lower alkylamine as a catalyst.
Dependencies are inferred from the claim text.