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US 5,344,842 AGranted
Thiosemicarbazone derivatives
AssigneeCiba-Geigy Corporation
InventorMartin Missbach
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AssigneeCiba-Geigy Corporation
InventorMartin Missbach
Estimating the term…
The invention relates to novel thiosemicarbazones of formula I ##STR1## wherein R.sub.1 is lower alkyl, lower alk-2-en-1-yl or lower alk-2-yn-1-yl, R.sub.2 and R.sub.3 independently of one another are hydrogen or lower alkyl, or R.sub.2 and R.sub.3 together are lower alkylidene, R.sub.4 is hydrogen, lower alkyl, lower alkoxy, aryl or aryl-lower alkyl, or the group --C(.dbd.O)--R.sub.6 wherein R.sub.6 is lower alkyl, aryl, heteroaryl, aryloxy, aryl-lower alkoxy or lower alk-2-en-1-yloxy, R.sub.5 is aryl, aryl-lower alkyl, unsaturated or saturated heterocyclyl-lower alkyl, lower alkoxycarbonyl-lower alkyl or the group --C(.dbd.O)--R.sub.7 wherein R.sub.7 is lower alkyl, aryl, aryl-lower alkyl, aryl-lower alkenyl, heteroaryl, aryloxy, aryl-lower alkoxy or lower alk-2-en-1-yloxy, or, when R.sub.4 is other than hydrogen, R.sub.5 may also be lower alkyl, lower alk-2-en-1-yl or lower alk-2-yn-1-yl, and to the salts thereof, to processes for the preparation of the said compounds, to pharmaceutical compositions comprising them and to their use as active ingredients in medicaments.
A compound of formula I ##STR13## wherein R.sub.1 is lower alkyl, lower alk-2-en-1-yl or lower alk-2-yn-1-yl,
A compound selected from the group consisting of
Dependencies are inferred from the claim text.