Sulfonamides as antifungal agents
AssigneeJ. Uriach & Cia. S.A.
InventorsJavier Bartroli, Manuel Anguita, Jordi Belloc, Elena Carceller, Carmen Almansa
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AssigneeJ. Uriach & Cia. S.A.
InventorsJavier Bartroli, Manuel Anguita, Jordi Belloc, Elena Carceller, Carmen Almansa
Estimating the term…
The present invention relates to new sulfonamides having the formula I: ##STR1## wherein: R.sup.1 represents an alkyl, aryl or heteroaryl group; R.sup.2 is hydrogen or an alkyl, aryl or heteroaryl group; or R.sup.1 and R.sup.2 may form a ring; R.sup.3 is hydrogen or may form an oxazolidine ring together with R.sup.2, and this ring may be optionally susbtituted by one or two alkyl, aryl or heteroaryl groups at the position 2; R.sup.7 is hydrogen or alkyl; X is CH or N; Ar is a phenyl ring or a substituted phenyl ring. The invention also relates to a procedure for their preparation and to pharmaceutical and agrochemical compositions containing them. These compounds are antifungal agents.
A compound of formula Ia:
5-(2,4-D ichlorophenyl)-3-methanesulfonyl-5-([1H-1,2,4-triazol-1-yl]methyl)oxazolidi ne.
(4R*,5R*)-5-(2,4-Dichlorophenyl)-3-methanesulfonyl-4-methyl-5-([1H-1,2,4-tr iazol-1-yl]methyl)oxazolidine.
(4R*,5R*)-5-(2,4-Difluoroph enyl)-3-methanesulfonyl-4-methyl-5-([1H-1,2,4-triazol-1-yl]methyl)oxazolidi ne.
Dependencies are inferred from the claim text.