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AssigneeHokuriku Pharmaceutical Co., Ltd.
InventorsHiroyuki Sawanishi, Yasuo Ito, Hideo Kato, Eiichi Koshinaka, Nobuo Ogawa, Kouji Morikawa
Estimating the term…
Novel polycyclic compounds represented by the following formula: A--(CH.sub.2).sub.n --COOR.sup.1, wherein R.sup.1 represents a hydrogen atom or a lower alkyl group; n represents an integer of from 0 to 5; and A is a group represented by the following formula: ##STR1## wherein X represents a hydrogen atom or a halogen atom; and Y represents a methylene group, an oxygen atom, or a sulfur atom, or A is a group represented by the following formula: ##STR2## and pharmacologically acceptable salts thereof are disclosed. Also disclosed are a method for preparing the same, a pharmaceutical composition comprising the same, an antiallergic agent and an agent for bronchial asthma comprising the same, and a method for treatment of an allergic disease or bronchial asthma comprising the step of administering the same.
A polycyclic compound represented by the following formula:
A polycyclic compound represented by the following formula:
A pharmaceutical composition comprising an effective amount of a polycyclic compound represented by the following formula:
A pharmaceutical composition comprising an effective amount of a polycyclic compound represented by the following formula:
4-(2-Chlorodibenz[b,f][1,4]oxazepin-11-yl)-1-piperazinepropionic acid and a pharmacologically acceptable salt thereof.
4-(2-Chlorodibenzo[b,f][1,4]oxazepin-11yl)-1-piperazinebutyric acid and a pharmacologically acceptable salt thereof.
4-(2-Chlorodibenzo[b,f][1,4]thiazepin-11-yl)-1-piperazinepropionic acid and a pharmacologically acceptable salt thereof.
4-(2-Chlorodibenzo[b,f][1,4]thiazepin-11-yl)-1-piperazinebutyric acid and a pharmacologically acceptable salt thereof.
4-(11H-Dibenz[b,e]azepin-6yl)-1-piperazinepropionic acid and a pharmacologically acceptable salt thereof.
4-(11H-dibenz[b,e]azepin-6-yl)-1-piperazinebutyric acid and a pharmacologically acceptable salt thereof.
Dependencies are inferred from the claim text.