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US 5,344,820 AGranted
Infection protectant
AssigneeSnow Brand Milk Products Co., Ltd.
InventorsShunichi Dosako, Hiroko Kusano, Eiki Deya, Tadashi Idota
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AssigneeSnow Brand Milk Products Co., Ltd.
InventorsShunichi Dosako, Hiroko Kusano, Eiki Deya, Tadashi Idota
Estimating the term…
Disclosed herein is an infection protectant which is excellent in infection protective effects and is also safe. .kappa.-Casein, a sialic-acid-conjugated protein derived from cow milk, and a glycomacropeptide derived from .kappa.-casein, each of which is useful as an active ingredient in this invention, have been found to be effective for the prevention of adhesion of E. coli on cells and also for the inhibition of transformation of lymphocytes by EBV and also to have strong HI activity against virus. The infection protectant of this invention is hence believed to exhibit marked effects for the prevention of occurrence of infectious diarrhea, for mass protection against spreading of influenza, and also against canceration of lymphocytes. Since the active ingredient of the infection protectant is a substance derived from cow milk, it is free of any problem from the viewpoint of safety. Moreover, it is absolutely tasteless and odorless. It can therefore be added to foods for its application.
A method for protection against gastrointestinal bacteria, Epstein-Barr and influenza viruses that comprises administering an effective amount of an isolated and purified sialic acid-conjugated peptide to a patient in need thereof, wherein the sialic acid-conjugated peptide is a glycomacropeptide obtained by reacting rennet or pesin with .kappa.-casein, cow milk, reconstituted milk or casein at pH 5.5-5.6.
Dependencies are inferred from the claim text.