Pharmaceutical compositions for use in treating inflammation
AssigneeAllelix Biopharmaceuticals Inc.
InventorGeoffrey L. Hammond
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Abstract
Inflammation in mammals is treated by administering anti-inflammatory agent complexed with corticosteroid binding globulin (CBG) that is produced by recombinant DNA-based techniques.
Claims18
A pharmaceutical composition useful in treating inflammation in a mammal, said composition comprising CBG, an anti-inflammatory agent having an affinity constant for CBG between 0.1 and 10 nM at about 4.degree. C. and physiological pH, and a pharmaceutically acceptable carrier, wherein said CBG is recombinant human CBG.
A method for treating inflammation in a human patient, comprising the step of administering to the patient a pharmaceutical composition comprising CBG, an anti-inflammatory agent having an affinity constant for CBG between 0.1 and 10 nM at about 4.degree. C. and physiological pH, and a pharmaceutically acceptable carrier, wherein said CBG is recombinant human CBG.
A pharmaceutical composition comprising recombinant human CBG, a stoichiometric excess of cortisol, and a pharmaceutically acceptable carrier.
Dependencies are inferred from the claim text.