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US 5,344,762 AGranted
Method for the early diagnosis of cancer
AssigneeERA-Masis, Ltd.
InventorAnait Karapetian
Life of this patent
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AssigneeERA-Masis, Ltd.
InventorAnait Karapetian
Estimating the term…
In a method for early diagnosis of human cancer, a human fecal sample of bacteria (Escherichia coli and/or Streptococcus faecalis), is incubated in vitro with a standard culture of a known number of cancer cells, for a period of time sufficient to enable the extent of interaction between the bacteria and the standard culture of cancer cells to be determined; the number of the interacted and/or non-interacted cancer cells present at the end of the period is determined and is utilized for the diagnosis based on the calculation of a tumor cell necrosis index (TCNI). The extent of interaction referred to may be calibrated against analogous interaction using a control preparation of bacteria, e.g. Escherichia coli A.T.C.C. 55373, 55374 and/or 55375, and/or Streptococcus faecalis A.T.C.C. 55376.
A method for the early diagnosis of cancer in a human, wherein a human feces-derived sample of bacteria selected from the group consisting of Escherichia coli and Streptococcus faecalis, is subjected to incubation in vitro with a standard culture of cancer cells containing a predetermined number of cancer cells, for a period of time sufficient to enable the extent of interaction between said bacteria and said standard culture of cancer cells to be determined, the number of the interacted and/or non-interacted cancer cells present at the end of the period of time being determined and being utilized for the purpose of said diagnosis based on the calculation of a tumor cell necrosis index (TCNI).
A method for the early diagnosis of cancer in a human, wherein a human feces-derived sample of bacteria selected from the group consisting of Escherichia coli and Streptococcus faecalis, is subjected to incubation in vitro with a standard culture of cancer cells containing a predetermined number of cancer cells, for a period of time sufficient to enable the extent of interaction between said bacteria and said standard culture of cancer cells to be determined, the number of the interacted and/or non-interacted cancer cells present at the end of the period of time being determined and being utilized for the purpose of said diagnosis based on the calculation of a tumor cell necrosis index (TCNI), and wherein said extent of interaction between said bacteria and said standard culture of cancer cells is calibrated against the extent of interaction between a control preparation of bacteria incubated under the same conditions and said standard culture of cancer cells.
A method for the early diagnosis of cancer in a human, wherein a human feces-derived sample of bacteria selected from the group consisting of Escherichia coli and Streiptococcus faecalis, is subjected to incubation in vitro with a standard culture of cancer cells containing a predetermined number of cancer cells, for a period of time sufficient to enable the extent of interaction between said bacteria and said standard culture of cancer cells to be determined, the number of the interacted and/or non-interacted cancer cells present at the end of the period of time being determined and being utilized for the purpose of said diagnosis based on the calculation of a tumor cell necrosis index (TCNI), wherein said extent of interaction between said bacteria and said standard culture of cancer cells is calibrated against the extent of interaction between a control preparation of bacteria incubated under the same conditions and said standard culture of cancer cells, and wherein in said control preparation of bacteria, there is used at least one strain selected from the group consisting of Escherichi coli A.T.C.C. 55373, Escherichia coli A.T.C.C. 55374, Escherichia coli A.T.C.C. 55375 and Streptococcus faecalis A.T.C.C. 55376.
Dependencies are inferred from the claim text.