Loading patent…
AssigneeHer Majesty the Queen in right of Canada, as represented by the Minister of Health & Welfare
InventorsAdalbert Laszlo, Vera Handzel
Estimating the term…
A method of testing for tuberculosis and leprosy in animals or humans and antigens used in the method. The method involves carrying out an assay on sera from humans or animals using an antigen to bind antibodies in sera. The antigens used in the method are synthetic pseudo cord factor-like glycolipids having the structures (I) or (II) below: ##STR1## wherein R represents a straight or branched chain alkyl group having 15 to 18 carbon atoms. The antigens can be produced by chemical synthesis, and can therefore be made available in suitable quantities, and are relatively stable at ambient temperatures while showing good sensitivity and specificity for tuberculosis and leprosy. The antigens can be used, for example, for enzyme-linked immunosorbent assays, and related "spot tests" for diagnosing tuberculosis and leprosy.
A method useful for the serodiagnosis of tuberculosis or leprosy in humans or animals suspected of being exposed to a bacterium selected from the group consisting of Mycobacterium tuberculosis and Mycobacterium leprae comprising:
An enzyme-linked immunosorbent assay test kit useful for the serodiagnosis of tuberculosis or leprosy in a human or animal suspected of being exposed to a bacterium selected from the group consisting of Mycobacterium tuberculosis or Mycobacterium leprae, comprising:
A spot test kit useful for the serodiagnosis of tuberculosis or leprosy in a human or animal suspected of being exposed to a bacterium selected from the group consisting of Mycobacterium tuberculosis or Mycobacterium leprae, comprising:
Dependencies are inferred from the claim text.