Production of vascular endothelial cell growth factor and DNA encoding same
AssigneeGenetech, Inc.
InventorsNapoleone Ferrara, David W.-H. Leung
Life of this patent
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Abstract
DNA isolates coding for a vascular endothelial cell growth factor may be used to produce the protein via recombinant expression systems. Such protein is useful therapeutically to treat conditions in which a selective action on the vascular endothelial cells, in the absence of excessive connective tissue proliferation, is desirable.
Claims12
An isolated DNA sequence comprising a nucleotide sequence encoding the amino acid sequence shown in FIG. 2 for bovine mature vascular endothelial cell growth factor.
An isolated DNA sequence comprising a nucleotide sequence encoding the amino acid sequence shown in FIG. 10 for human mature vascular endothelial cell growth factor.
Dependencies are inferred from the claim text.