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US 5,236,703 AGranted
Polymeric substrates containing povidone-iodine as a control release biologically active agent
AssigneeVirex Inc.
InventorAnton-Lewis Usala
Life of this patent
Estimating the term…
Abstract
A polymeric substrate such as rubber or latex incorporates povidone-iodine as a control release biologically active agent.
Claims10
A polymeric film which control-releases a biologically active agent while in contact with a polar liquid to prevent the contamination and penetration of pathogens through said film, comprising:
- at least one layer of said polymeric film having dispersed therein povidone-iodine in the range of about 0.01% to 25% as said biologically active agent;
- said polymeric film prepared from a dispersion of said povidone-iodine and a film-forming polymeric material prepared by homopolymerization or copolymerization of ethylene monomers or monomers having at least two conjugated double bonds and capable of being vulcanized or cross-linked, said polymeric film being heated at elevated temperatures for a length of time varying with respect to the temperature and the amount of said povidone-iodine to control the release of said povidone-iodine from said film upon contact with said polar liquid.
A latex substrate comprising:
- a heat cured latex rubber having bonded thereto a predetermined amount of povidone-iodine substantially through van der Waals bonds by controlled heating thereby enabling local release of said povidone-iodine therefrom upon contact with a polar liquid, said predetermined amount being in the range of about 0.01% to 25%.
A latex substrate comprising:
- a film layer of cured latex rubber incorporating povidone-iodine therewithin formed from a mixture comprising said latex rubber and said povidone-iodine, said mixture being processed to a predetermined exclusion of covalent bonding between said latex rubber and said povidone-iodine, said povidone-iodine being present in the amount of about 0.1% to 10%.
A latex rubber substrate comprising:
- a latex rubber and an effective amount of povidone-iodine formed from a mixture comprising said latex and said povidone-iodine, said povidone-iodine being in the amount of about 0.01% to 25% and functioning as a vulcanizing and cross linking agent upon heating of said mixture at temperatures below about 400.degree. to permit release of said povidone-iodine as an antimicrobial upon contact with a polar liquid.
A multilayer latex article comprising:
- a plurality of heat cured latex rubber substrate films, at least one of said films being a controlled release film having incorporated therewithin povidone-iodine in the range of about 0.01% to 25%, said povidone-iodine in said controlled release film having controlled van der Waals bonding with said latex.
Dependencies are inferred from the claim text.