US 5,217,426 AGranted

Combination disposable plastic blood receiving container and blood component centrifuge

AssigneeBaxter International Inc.

InventorsDavid V. Bacehowski, Herbert M. Cullis, Armand R. VanBaelen

Life of this patent

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Abstract

A blood component separating device comprises a centrifuge bowl adapted for rotation about its axis in a centrifuge. The bowl defines an outer arcuate wall plus an inner circumferential wall, spaced from the outer wall, to define a arcuate slot adapted for receiving blood components. Access tubing is adapted for communication with the slot. Preferably, an elongated, flexible, collapsible inner liner is provided in the slot. Individual access tubing also may communicate with an elongated container interior between the ends of the elongated, collapsible container. Furthermore, a portion of the slot may define the shape of an outwardly extending spiral, to provide an increasing gravitational field upon fluids therein as the fluid moves along the slot.

Claims45

Dependent claims

The combination of a disposable container and a centrifuge, said combination comprising,

a rotor;
means defining a generally annularly extending multiportion processing channel in said rotor for processing a suspension including at least one cell component;
said channel including one portion for performing a separation function;
said channel including another portion for performing another separation function, said other portion being generally spiral-like relative to the true center of said rotor;
a disposable plastic suspension-receiving container disposed within said one and other portions of said channel;
and
fluid connection means at separated locations of said container for introducing the suspension into and extracting at least one suspension component from said container, said fluid connection means including:
a first fluid connection means;
(a) communicating with the part of said container disposed in said other portion of said channel,
(b) being adapted for extracting a first suspension component from the part of said container disposed in said other portion of said channel, and
(c) being located at a greater radial distance from the true center of the rotor than the radial distance where the first suspension component enters the part of said container disposed in said other portion of said channel.

8 more elements

The combination of a disposable container and a centrifuge, said combination comprising:

a rotor;
means providing a generally annularly extending multiportion processing channel in said rotor for processing a suspension including at least one cell component;
said channel including one portion for performing a separation function;
said channel including another portion for performing another separation function, said other portion being generally spiral-like relative to the true center of said rotor;
said multi-portion processing channel having a total arc that is no greater than 360.degree.;
a disposable plastic suspension-receiving container disposed within said one and said other portions of said channel;
and
fluid connection means at separated locations of said container for introducing the suspension into and extracting at least one suspension component from said container.

5 more elements

The combination of a disposable container and a centrifuge, said combination comprising:

a rotor;
means providing a generally annularly extending multiportion processing channel in said rotor for processing a suspension including at least one cell component;
said channel including one portion for performing a separation function;
said channel including another portion for performing another separation function, said other portion being generally spiral-like relative to the true center of said rotor;
said multi-portion processing channel having a total arc that is no greater than 360.degree.;
a disposable plastic suspension-receiving container disposed within said one and other portions of said channel;
fluid connection means at separated locations of said container for introducing the suspension and extracting components of the suspension from said container;
said fluid connection means comprising a first fluid connection for introducing the suspension, a second fluid connection for extracting a first suspension component, a third fluid connection for extracting a second suspension component and a fourth fluid connection means for extracting a third component of the suspension;
one of said fluid connection means for extracting a suspension component (a) communicating with the part of said container disposed in said other, spiral-like portion of the channel (b) being adapted for extracting a suspension component from said container, and (c) being located at a greater radial distance from the true center of the rotor than the radial distance where the suspension component enters the part of said container disposed in said other, spiral-like portion of said channel.

6 more elements

Dependencies are inferred from the claim text.

Facts

Application: 07/744,947Filed 14 Aug 1991 · continuation
Priority: 12 Aug 1977
Granted: 8 Jun 1993
Term ends: Not estimatedThe source records don’t support an estimate.

Classification12 codes

C07K 16/06
Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies: from serum
B04B 1/00
Centrifuges with rotary bowls provided with solid jackets for separating predominantly liquid
B04B 5/0428
For liquids contained in receptacles: with flexible receptacles
B04B 5/0442
Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers: with means for adding or withdrawing liquid substances…

Family

Serial824,182Parent of this division · filed 12 Aug 1977
Serial463,694Parent of this division · filed 11 Jan 1990
Serial660,710Parent of this continuation · filed 25 Feb 1991
US 5,006,103 AParent of this division
US 4,934,995 AParent of this division
US 5,217,426 AThis patent

From the US filing history. Foreign family members aren’t listed.