Lubricious hydrogel coatings
AssigneeC. R. Bard, Inc.
InventorRichard K. Elton
Life of this patent
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Abstract
A flexible, lubricious organic coating is formed by applying a mixture of an isocyanate, a polyol, polyvinylpyrrolidone (PVP), and carrier liquid to a surface to be coated. The carrier liquid is removed and the mixture reacted to form a lubricious, flexible coating, particularly suitable for use as a protective lubricious caoting on medical devices introduced into the body. The coating exhibits a significantly reduced coefficient of friction when exposed to water or aqueous solutions.
Claims16
An article comprising a substrate on which is coated a hydrophilic, lubricious, organic coating comprising a crosslinked polyurethane and a polyvinylpyrrolidone, said crosslinked polyurethane formed from the reaction of an isocyanate and a polyol, said isocyanate containing at least two NCO groups per molecule and the polyol having at least two hydroxy groups per molecule, the sum of the average NCO functionality and the average hydroxy functionality exceeding 4.
An article comprising an organic substrate and a hydrophilic, lubricious organic coating adhered thereto, said coating formed from the reaction on the surface of the substrate to be coated, of a mixture comprising an isocyanate, a polyol and polyvinylpyrrolidone in a carrier liquid to form a crosslinked polyurethane-polyvinylpyrrolidone coating, said isocyanate containing at least two NCO groups per molecule and the polyol having at least two hydroxy groups per molecule, the sum of the average NCO functionality and the average hydroxy functionality exceeding 4.
Dependencies are inferred from the claim text.