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AssigneeCetus Corporation
InventorsManinder Singh, Jack H. Nunberg, Thomas R. Tice, Michael E. Hudson, Richard M. Gilley, Terrance A. Taforo
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Shipping fever, and other stress-related diseases in livestock, are treated by administration of a microencapsulated composition comprising IL-2 conjugated with a polyoxyethylene polymer, and mixed with a release-modulating amount of humen serum albumin. The microcapsules are administered parenterally, and release an effective amount of conjugated IL-2 continuously over a period of 14-30 days. These microcapsules are also effective in the treatment of cancer in mammals.
A composition for continuously delivering a relatively constant, effective amount of PEGyl-IL-2 comprising:
A formulation for administering IL-2 or an IL-2 equivalent continuously over a period of 14-30 days, which formulation comprises:
Dependencies are inferred from the claim text.