Stabilized sucralose complex
AssigneeWarner-Lambert Company
InventorsSubraman R. Cherukuri, Lucy L. Wong
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Abstract
The chlorosucrose sweetener known as sucralose is prepared in a thermally stable composition by co-crystallization with a cyclodextrin. The resulting crystalline product may be comminuted to form particles of desired size for use as a sweetener component in place of or in addition to known sweeteners such as sucrose, saccharin and the like, in a variety of foods, comestibles, and oral medications. The preparation of the stabilized sucralose compositions of the present invention constitutes a molecular encapsulation of the sucralose within the cyclodextrin thereby protecting the sucralose from discoloration caused by heat. Numerous applications for this stabilized complex are suggested and disclosed.
Claims25
A thermally stabilized sucralose composition comprising a co-crystallized complex of sucralose and at least about 5% by weight of a cyclodextrin.
A method for the preparation of a thermally stabilized sucralose composition, comprising:
- (a) dissolving a quantity of sucralose and a stoichiometrically sufficient amount of a cyclodextrin in a suitable non-aqueous solvent;
- (b) maintaining the solution formed in step (a) for a period of time sufficient to permit full co-crystallization of said sucralose and said cyclodextrin to take place;
- (c) recovering the crystalline reaction product from step (b) and drying the same;
- and
- (d) subjecting the material from step (d) to comminution to form particles therefrom.
Dependencies are inferred from the claim text.