Self-adhesive plaster containing medication
AssigneeBeiersdorf AG
InventorsErich Nick, Gunter Guse, Bodo Asmussen
Life of this patent
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Abstract
A self-adhesive medicinal plaster comprises a plurality of adhesive elements spaced from each other on a surface of a carrier web and a plurality of active ingredient elements, containing a medication, spaced from each other and from the active ingredient elements on the surface of the carrier web whereby the medicinal active ingredient composition is isolated from the adhesive composition.
Claims21
A self-adhesive transdermal medicinal plaster in which the medication is isolated from the adhesive, comprising:
- (a) an impermeable carrier web;
- (b) a plurality of adhesive elements spaced from each other at predetermined locations on a surface of said carrier web;
- and
- (c) a plurality of active ingredient elements, containing at least one transdermal medication, spaced from each other and from said active ingredient elements at predetermined locations on said surface of said carrier web;
- (d) said active ingredient elements being disposed between a plurality of said adhesive elements and said adhesive elements being disposed between a plurality of said active ingredient elements on said surface of said carrier web, and the height of said active ingredient elements and the height of said adhesive elements on said carrier web being about the same to assure, when said plaster is applied to the skin, uniformly good contact of both said active ingredient and adhesive elements with the surface of the skin.
A self-adhesive medicinal plaster according to claim 5 wherein each of said adhesive elements and each of said medicinal active ingredient elements are approximately cap-shaped and adhere at its base to said surface of said carrier web.
A self-adhesive medicinal plaster according to claim 5 wherein each of said medicinal active ingredient elements is surrounded by a plurality of said adhesive elements and each of said adhesive elements is surrounded by a plurality of said medicinal active ingredient elements.
A method of making a self-adhesive transdermal medicinal plaster in which the medication is isolated from the adhesive, comprising applying, by gravure printing processes, a dispersion, plastisol or organisol of an adhesive having a high solids content and a dispersion of at least one transdermal medication having a high solids content at spaced locations on one surface of an impermeable carrier web and drying said adhesive and said medication to form a plurality of adhesive elements and a plurality of transdermal medicinal active ingredient elements spaced from each other at predetermined locations on said surface of said carrier web, said elements being arranged such that each of said medicinal active ingredient elements is disposed between a plurality of said adhesive elements and each of said adhesive elements is disposed between a plurality of said medicinal active ingredient elements, the amount of dispersion, plastisol or organisol of said adhesive and the amount of said dispersion of at least one medication applied to said carrier web being such that the height of the resultant adhesive elements and the height of the resultant active ingredient elements on said carrier web are about the same to assure, when said plaster is applied to skin, uniformly good contact of both said adhesive and active ingredient elements with the surface of the skin.
A method of making a self-adhesive plaster according to claim 19 wherein said gravure printing processes are screen printing processes.
A method of making a self-adhesive plaster according to claim 19 wherein said adhesive applied to said carrier web is an aqueous, thixotropic dispersion of adhesive with a solids content of 55-65% by weight.
A method of making a self-adhesive plaster according to claim 19 comprising first applying said adhesive to said carrier web, drying said adhesive to form said plurality of adhesive elements, and cross-linking the composition of said adhesive elements and then applying said medication to form said medicinal active ingredient elements and drying said medicated active ingredient elements.
Dependencies are inferred from the claim text.