Preparation of tetrahydroisohumulones
AssigneeMiller Brewing Company
InventorsJohn M. Cowles, Henry Goldstein, Etzer Chicoye, Patrick L. Ting
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Abstract
Tetrahydroisohumulones are prepared from beta-acids without using objectionable organic solvents by treating the beta-acids to form desoxytetrahydrohumulones which are dissolved in an aqueous alcoholic caustic solution and then oxidized and isomerized with an oxygen-containing gas in the presence of metallic ion to form the desired tetrahydroisohumulones.
Claims5
A method of preparing tetrahydroisohumulones directly from desoxytetrahydrohumulones without isolating the intermediate tetrahydrohumulones which comprises dissolving desoxytetrahydrohumulones in an aqueous caustic ethanol solution having a pH of about 8 to about 12, said solution containing an effective amount of a metallic isomerization catalyst to immediately catalyze the isomerization of any tetrahydrohumulones formed to tetrahydroisohumulones, said solution and said catalyst being free of lead ions;
- bubbling an oxygen-containing gas through the solution while heating the solution to about 40.degree. C. to about 65.degree. C. to oxidize the desoxytetrahydrohumulones to tetrahydrohumulones which are immediately and selectively isomerized to tetrahydroisohumulones before the tetrahydrohumulones can be further oxidized.
Dependencies are inferred from the claim text.