Collagen replacement prothesis for the cornea
AssigneeMassachusetts General Hospital
InventorsRomaine R. Bruns, Jerome Gross
Life of this patent
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Abstract
This invention relates to a prosthetic replacement for the cornea and particularly to a transparent collagen material useful for making such a prosthesis and to methods for making such transparent collagen material. The prosthesis is preferably composed of a native, non-fibrilized, transparent collagen material formed from a soluble collagen solution by ultracentrifuging to form a pellet and fixing the same pellet, whereby the collagen material has less than 5% absorbance of light at 900 nm for a 5 mm thick sample and comprises polyhydroxyethylmethacrylate or vitrosin, in a range of from 0.01 to 50.0 percent by weight, based on the collagen protein.
Claims4
A prosthetic cornea replacement comprising collagen wherein the collagen component consists essentially of a native, non-fibrillized, transparent, crosslinked collagen material that has less than 5% absorbance of light at 900 mm for a 5 nm thick cross section.
A native, non-fibrilized, transparent collagen material formed from a soluble collagen solution by ultracentrifuging to form a pellet and fixing said pellet, said collagen material having less than 5% absorbance of light at 900 nm for a 5 mm thick sample and comprising polyhydroxyethylmethacrylate or vitrosin, in a range of from 0.01 to 50 percent by weight, based on the collagen protein.
Dependencies are inferred from the claim text.