Rapidly disintegrable tablet composition and method
OwnerJoseph Michaelsoninventor
Life of this patent
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Abstract
Rapidly water-disintegrable tablet is provided comprising an active ingredient such as a foodstuff or medicament, and distributed therewithin a small but effective amount of a tablet disintegrable system comprising an unreacted, intimate mixture of alginic acid and a water soluble metal carbonate in proportions reactive to form metal alginic acid salt and carbonic acid when the tablet is placed in water, the bulk of the salt acting to swell the tablet and the carbonic acid acting to simultaneously release carbon dioxide within the swelling tablet whereby rapid disintegration of the tablet is effected.
Claims19
Rapidly water-disintegrable tablet comprising an active ingredient, and distributed therewithin a small but effective amount of a tablet disintegrable system comprising an unreacted, intimate mixture of alginic acid and a water soluble carbonate radical precursor in proportions reactive to form metal alginic acid salt and carbonic acid when the tablet is placed in water, the bulk of said formed salt acting to swell the tablet and the carbonic acid acting to simultaneously release carbon dioxide within the swelling tablet whereby rapid disintegration of the tablet is effected, the alginic acid salt acting to body the resulting active ingredient solution.
Rapidly water-disintegrable tablet comprising an active ingredient, and distributed therewithin an effective amount of a tablet disintegrable system comprising an unreacted, intimate mixture of alginic acid and a water soluble metal carbonate in proportions reactive to form metal alginic acid salt and carbonic acid when the tablet is placed in water, said alginic acid comprising from 3 to 15% and the metal carbonate from 1 to 70% of the tablet by weight, the bulk of the salt formed acting to swell the tablet and the carbonic acid acting to simultaneously release carbon dioxide within the swelling tablet whereby rapid disintegration of the tablet is effected, said alginic acid salt acting to body the resulting active ingredient solution.
Method of preparing a rapidly water-disintegrable tablet, including combining an active ingredient with a small but effective amount of an unreacted mixture of a water soluble metal carbonate and alginic acid, intimately and under pressure, pulverizing, and tabletting with a lubricant as necessary to form a stable tablet.
Dependencies are inferred from the claim text.