Synthesis of substituted phenols
AssigneeFisons Limited
InventorsDavid K. Rainey, Michael M. Fanthorpe
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Abstract
There is described a process for the production of a 4,6-diacetyl resorcinol having an alkyl C 1 to 6 or an alkenyl C 2 to 6 group in the 2-position, which comprises reacting 4,6-diacetyl resorcinol with an alkyl C 1 to 6- or an alkenyl C 2 to 6- halide. The product 4,6-diacetyl resorcinols are useful as intermediates in the production of pharmaceuticals. Certain of the product 4,6-diacetyl resorcinols are novel.
Claims6
A process for the production of a compound of formula I, ##STR3## in which R.sub.1 is alkyl C 1 to 6, which comprises reacting 4,6-diacetyl resorcinol with an alkyl C 1 to 6- bromide or iodide in a polar hydrogen bonding solvent at a temperature of from 20.degree. to 120.degree. C.
2-Allyl-4,6-diacetyl resorcinol or 2-iso-propyl-4,6-diacetyl resorcinol.
Dependencies are inferred from the claim text.