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US 4,400,534 AGranted
Analgesic and anti-inflammatory agents
AssigneeSankyo Company, Limited
InventorsAtsusuke Terada, Eiichi Misaka
Life of this patent
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Abstract
Compounds of formula (I): ##STR1## its salts, and resolved forms thereof, especially the compound of formula (II): ##STR2## and its salts are new analgesic and/or anti-inflammatory agents. The agents are prepared by resolution at the 2-position of a suitable starting material such as the compound (IV): ##STR3## or an optionally partly resolved form thereof, with subsequent reduction and optional resolution to give the trans form.
Claims5
(2S)-2-[4-(2-hydroxycyclopentan-1-ylmethyl)phenyl]propionic acid of the formula (I):
- ##STR8## or a pharmaceutically active salt thereof.
(2S)-2-{4-[(2S,1R)-2-hydroxycyclopentan-1-ylmethyl[phenyl}propionic acid of the formula (II):
- ##STR9## or a pharmaceutically active salt thereof.
Dependencies are inferred from the claim text.