Benzylidene derivatives
AssigneeSynthelabo
InventorsJean-Pierre Kaplan, Naurice Jalfre, Don P. Giudicelli
Life of this patent
Estimating the term…
Loading patent…
AssigneeSynthelabo
InventorsJean-Pierre Kaplan, Naurice Jalfre, Don P. Giudicelli
Estimating the term…
Compounds of the formula: ##STR1## in which X.sub.1, X.sub.2 and X.sub.3, which are identical or different, each represent hydrogen, halogen, methyl, or methoxy, n represents an integer from 1 to 10, and R represents hydroxyl, OM, NH.sub.2, NH(CH.sub.2).sub.3 --COOH, --NH(CH.sub.2).sub.3 --COOM, (where M represents an alkali metal atom), NH(CH.sub.2).sub.3 --COOC.sub.2 H.sub.5, NH-cycloalkyl, NH-phenyl, NH-benzyl (where the benzyl radical is unsubstituted or substituted by halogen or trifluoromethyl), NH-alkyl, N(alkyl).sub.2 and N-(alkyl)-(benzyl), the aforesaid alkyls being straight or branched and having from 1 to 4 carbon atoms and the aforesaid cycloalkyls having from 3 to 6 carbon atoms, except that when X.sub.1 and X.sub.3 are both hydrogen, n is 1 and R is OH, X.sub.2 is not chlorine in the 5-position are useful in the treatment of epilepsy by oral or parenteral administration.
A compound of the formula:
A pharmaceutical composition for the treatment of epilepsy or convulsions in dosage unit form comprising a compound of the formula:
A method of relieving convulsions or epilepsy in a patient which comprises administering to said patient an anti-convulsively or anti-epileptically effective amount of a compound of the formula:
Dependencies are inferred from the claim text.